Doreen is the mother of Stuart Larkin. It is mentioned many times that she is an alcoholic. (Although some would say semi-drunk). Her husband left her on Tuesday. She is in love with (or flirts with, not necessarily in love with) her obese neighbor Harvey Muckenthaler. She appears in many episodes. She is rather over-protective of her son and refuses to acknowledge his bad behavior towards, for instance, strangers. She is hilarious. Doreen also has a sister named Colleen who was abandoned at the altar by her fiancee, Gordon, who became fearful of their children turning out like Stuart.
She is played by comedic genius Mo Collins.